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Similarly, naroparcil had no effect on APTT nor on thrombin time. A sensitized thrombin time (to about 35 s) was modestly but drastically amplified following oral administration with the compound at four hundred mg/kg. On the other hand, thrombin era from the intrinsic pathway was reduced within a dose-similar way, with maximal reduction being sixt

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In the beginning, we executed experiments with different concentrations of inhibitors and doses of IR. Spautin-1 was selected like a Manage in proliferation analyzing the methods. To be able to Evaluate the general inhibition influence of the researched autophagy inhibitor—Lys05, we utilised the inhibitor possessing another system of action (comp

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